Detection of Cytomegalovirus (CMV) in Peripheral Blood Specimens in Patients before Keratoplasty

نویسندگان

  • Fariba Sheikhi-Shooshtari Department of Ophthalmology, Faculty of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran
  • Jalil Omidian Department of Ophthalmology, Faculty of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran
  • Maryam Fazeli WHO Collaborating Center for Reference and Research on Rabies, Pasteur Institute of Iran, Tehran, Iran
چکیده مقاله:

Cytomegalovirus is the most important pathogen affecting transplant recipients and causing significant morbidity and morbidity. The prevalence of CMV  infections in transplant recipient varies from country to country.  The aim of this study was to determine the prognostic value of PCR assay for CMV  detection in patients before Keratoplasty.  A total of 23 patient samples enrolled in this study from March 2008 to Feb 2010.  Based on the result the over all incidence of CMV  infection was 39.1 percent (9 positive sample) in PCR assay.  In this study, the plasma PCR assay proved to be sensitive and specific in order to detect CMV  infections.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

detection of cytomegalovirus (cmv) in peripheral blood specimens in patients before keratoplasty

cytomegalovirus is the most important pathogen affecting transplant recipients and causing significant morbidity and morbidity. the prevalence of cmv  infections in transplant recipient varies from country to country.  the aim of this study was to determine the prognostic value of pcr assay for cmv  detection in patients before keratoplasty.  a total of 23 patient samples enrolled in this study...

متن کامل

Cytomegalovirus (CMV) blood DNA load, CMV retinitis progression, and occurrence of resistant CMV in patients with CMV retinitis.

BACKGROUND The amount of cytomegalovirus (CMV) DNA in the blood (CMV load) may be a marker for detection of resistant CMV.METHODS. A total of 165 patients with AIDS and CMV retinitis had CMV load measurements (plasma and leukocyte) and cultures performed every 3 months; these measurements were correlated with CMV resistance to antiviral drugs and CMV retinitis progression (from masked readings ...

متن کامل

Evaluation of the AMPLICOR CMV test for direct detection of cytomegalovirus in plasma specimens.

We evaluated the AMPLICOR CMV test (PCR) for the direct detection of cytomegalovirus in plasma. Sixty-eight specimens were involved for the comparison between the AMPLICOR test and the antigenemia assay. The sensitivities, specificities, and positive and negative predictive values were 97.1, 100, 100, and 97.1%, respectively, for the AMPLICOR test and 79.4, 100, 100, and 82.9%, respectively, fo...

متن کامل

Frequency of Cytomegalovirus (CMV) in benign and malignant tumors

Cytomegalovirus (CMV) is a widespread pathogen that is found in milk, saliva, urine, cervical secretions, and semen fluid. It is supposed that CMV is a risk factor for breast cancer. The aim of this study was to determine the frequency of CMV among benign and malignant breast tumors. Paraffin embedded breast carcinoma (n=24) and fibroadenoma (n=24) samples were collected from Toos and Firoozgar...

متن کامل

Cytomegalovirus (CMV) Encephalitis in HIV Patients

It is hypothesized that impaired CD4 cell functioning is attributable to viral replication. Most cases of CMV encephalitis occur when CD4 counts fall below 50, however patients may be predisposed to CMV infection prior to depletion of CD4 [1]. Previous opportunistic infections (OIs), a high level of CMV viremia, and high plasma HIV RNA levels (>100,000 copies/mL) are other reported risk factors...

متن کامل

Immunophenotype of peripheral blood lymphocytes following thermal injury in patients

AbstractBackgroundcontributes substantially to patient morbidity and mortality.In this study we investigatedthe range and distribution of T-lymphocyte. Subsets CD3helper/inducer cell,.th ), CD8: Severe immunosuppression occurs after large thermal burn and probably+ (T cells) CD4+ (T+ (T suppressor /Cytotoxic cells ,TS/C), CD3+CD4thermal injury.+/CD3+CD8+ ratio, CD19+ (B cells) and CD16+ (NK cel...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ذخیره در منابع من قبلا به منابع من ذحیره شده

{@ msg_add @}


عنوان ژورنال

دوره 10  شماره None

صفحات  58- 62

تاریخ انتشار 2016-09

با دنبال کردن یک ژورنال هنگامی که شماره جدید این ژورنال منتشر می شود به شما از طریق ایمیل اطلاع داده می شود.

کلمات کلیدی

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023